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Wanderers pulled a goal back just before the break but couldn't find a way past Ola Tidman in the Wednesday goal for a deserved equaliser.
Team news saw Richard Harris return to the starting line-up following a hamstring injury. He replaced Simon Patterson who didn't even make it onto the bench. Elsewhere Frank Talia retained his place in goal, while Steve Dell was favoured ahead of Danny Senda at right back and Charlie Mapes preferred to Dannie Bulman in midfield.
After conceeding nine goals in the previous three games the opening minutes were a disaster for Wycombe. Former Brentford striker Lloyd Owusu headed the visitors into the lead in the 5th minute and three minutes later the same player crossed from the right for Alan Quinn to slot past a stranded Frank Talia. In between the goals Charlie Mapes went close with a shot from a Darren Currie from the right but at the other end Talia had to be quick off his line to block Grant Holt as Wednesday threatened to run riot.
A cross from Harris on the right after 30 minutes saw claims for handball waved away by referee Dermot Gallagher before Wanderers survived another scare in front of their own goal when Quinn's shot from the right deflected off Roger Johnson and brushed the side netting.
Wanderers eventually pulled a goal back four minutes before the break when Jermaine McSporran smashed a loose ball in at the far post after Chris Vinnicombe's left wing cross had been sent goalwards amongst a melee of players.
The goal proved an immediate boost for Wycombe and Iffy Onuora had a great chance to level on the stroke of half-time after Darren Currie had delivered from the right side of the penalty area but the on loan Sheffield United striker seemed to delay too long and the chance was blocked.
Half-time Wycombe 1 Wednesday 2
After the interval Wycombe went on to enjoy their fair share of the possession after but couldn't find that vital touch in front of goal. Currie went close with a free-kick just before the hour mark and a series of long throws by Harris failed to cause any real problems for Wednesday's defence.
It was Harris who went the closest to an equaliser in the 65th minute when he saw a shot on the run from McSporran's flick on forced over the cross bar by the legs of Tidman. Then after Senda had replaced Steve Dell it was Harris who should have been better placed to receive Senda's low cross from the right on 81 minutes.
A minute later Wednesday had Derek Geary sent off for a rash challenge on Chris Vinnicombe but Wycombe couldn't take advantage of the extra man with substitute Jonny Dixon seeing a low shot saved to the keeper's right in stoppage time as Wanderers last chance of snatching a point evaporated.
Final Score - Wycombe 1 Sheffield Wednesday 2
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